Give the BNAT exam to get a 100% scholarship for BYJUS coursesNo worries! Mouse urine and pelt proteins are an allergic hazard to people. D. If an IACUC votes to suspend a protocol or animal activity, that decision can be overturned by any administrator at the organization. To provide assistance with alternatives and database searches. All answers are correct. AAALAC stands for the Association for Assessment and Accreditation of Laboratory Animal Care. More than 850 companies, universities, hospitals, government agencies and other research institutions in 36 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. Quickly and professionally. The skin should be disinfected around the incision site. : Which statement is true about mice in the age range of 11 to 14 days? More than 1,000 companies, universities, hospitals, government agencies and other research institutions in 47 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. Pain or distress in mice is commonly expressed by dramatic changes in activity level and behavior. What statement regarding adjunctive methods of euthanasia is TRUE? Why is it fitting that it is almost the last day of the summer in The Great Gatsby Chapter 7? A. A mouse with a moderately painful condition may appear and behave normally. A public relations specialist is not part of this mandate. Which of the following statements is true regarding research antibody production? A. C. Once respiration stops in mice euthanatized with carbon dioxide, it is safe to assume that death has occurred, and mice may be placed in an airtight bag and transferred to the necropsy refrigerator. (1) If, in the opinion of the attending veterinarian, it is inappropriate for certain dogs to exercise because of their health, condition, or well-being, the dealer, exhibitor, or research facility may be exempted from meeting the requirements of this section for those dogs(2) A research facility may be exempted from the requirements of this section if the principal investigator determines for scientific reasons set forth in the research proposal that it is inappropriate for certain dogs to exercise." An agent that has high individual risk but low community risk would be in which Risk Group per the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules? The Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching (the Ag Guide) Lethal dose experiments in which animals are allowed to die without intervention. A. They have potential biological warfare uses. C Sterile surgical techniquethe goal of which is to prevent contamination of the surgical siteis required for major and minor survival surgery. Wild birds. Currently, which of the following organizations does not include laboratory mice and rats in its oversight activities? Which of the following statements about the postoperative period is false? B. Who is generally given institutional responsibility for deciding if an individual researcher is properly trained to perform animal procedures, as required by law? Before any use of the animals for the project begins. If a procedure would be painful in a human, one should assume that it would be painful in an animal. D. Animals must be moved to larger cages. How are Salmonella spp. Fell free get in touch with us via phone or send us a message. Which of the following is NOT an example of reduction per the three Rs of Russell and Burch? A practicing scientist with experience in animal research, person who is not a scientist, person who is not affiliated with the organization, and public relations specialist. Write the mass number, atomic number, and symbol for the remaining particle.\ However, the latter should be performed under anesthesia and is not a preferred site because of the potential for damage to the eye when the technique is not done properly or when used repeatedly. The fur should What is the goal of an occupational health and safety program? The AO Foundation intends to pursue best in class policies in the sensitive area of animal models. Which of the following is true of AAALAC International? The IACUC can exempt an animal for scientific reasons. B. The IACUC A. Participation as a Member Organization demonstrates commitment to the responsible and humane use of animals in science. Techniques for creating transgenic animals D. Supportive care and monitoring can be discontinued when the mice have recovered from anesthesia. which of the following is true of aaalac international? C. Those organizations that accept U.S. Department of Agriculture (USDA) research funds. What is the basis for the pain/distress classification system used by most institutions? C. Typical services include rabies immunizations, tuberculosis testing, and tetanus immunizations. AAALAC International accreditation is recognized around the world as a symbol of high quality animal care and use for research, teaching and testing, as well as promoting animal welfare. A dedicated surgery suite must be used for which surgery? Along with meeting all applicable local and national regulations, AAALAC accredited institutions must also demonstrate that they are achieving the standards outlined in the Guide for the Care and Use of Laboratory Animals (National Research Council, 1996). Along with meeting all applicable local and national regulations, AAALAC accredited institutions must also demonstrate that they are achieving the standards outlined in the Guide for the Care and Use of Laboratory Animals (Guide, NRC 2011); the Guide for the Care and Use of Agricultural Animals in Research and Teaching (Ag Guide, FASS 2010); and the European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes, Council of Europe (ETS 123). D. Rodents and rabbits. B. The organization and regulatory agencies only The IACUC's activities to ensure compliance benefit whom? Those organizations that conduct wildlife research. Office of Laboratory Animal Welfare (OLAW) The European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes, Council of Europe (ETS 123). Weve got your back. What is a safe bleed volume for a 20-gram mouse? It uses mice to grow hybridoma cells on their peritoneal lining. C. The IACUC has regulatory authority to stop any animal activities to protect either animals or people. Over distension of the urinary and gall bladders. This concept represents the beginning of the effort to form an accreditation program for laboratory animal care and use. Any time before the results are submitted for publication. B. Humane methods of animal experimentation If the investigator believes the event is due to misuse, mistreatment, or noncompliance, the details of the incident should be reported to the IACUC (or use another reporting method recommended by their organization), so that the incident can be reviewed and investigated (if warranted). D. Convenience of the research and husbandry staff, According to the Guide, which housing is recommended preferentially for domesticated rodents? A total number of 15 lines (5 + 4 + 3 + 2 + 1) will be obtained in this Who better to ask than your local auto body shop? The Guide for the Care and Use of Laboratory Animals (the Guide, NRC 2011); The Guide for the Care and Use of Agricultural Animals in Research and Teaching (the Ag Guide, FASS 2010); and. Which of the following best summarizes the information that must be provided when a database search is used to document a lack of alternatives? A change from non-survival to survival surgery B. A narrative summarizing experimental data that justifies the use of the proposed animal model. B. Sponsors an accreditation program Sedation causes vasodilation which helps make the tail vein easier to find. B. A. A. Which of the following statements regarding the use of restraint on animals in a research study is FALSE? Obtain approval of the animal husbandry staff. Dont worry, you wont be the first person to ask. Some use accreditation as a symbol of qualityit shows that an institution is serious about setting, achieving and maintaining high standards for animal research programs. B. C. While under anesthesia, mice should be monitored for cardiovascular and respiratory function and body temperature. When picking up a mouse from a filter top cage, putting the wire bar lid sideways on the cage is helpful to: Reposition your grasp as you take the mouse out of the cage as it will tend to hold on to the wire bar lid. According to the Guide, social animals should be housed in pairs or groups whenever possible. The Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC) is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. ), "Exemptions. These "Member Organizations" include the American Heart Association, American Veterinary Medical Association, Asian Federation of Laboratory Animal Science Associations, European Society of Laboratory Animal Veterinarians, the National Association for Biomedical Research, and the Society of Toxicology. D. The use of computer modeling software to substitute for animal experiments. Inoculation of recombinant infectious agents into animals. Locked bedroom doors are a common sight in many homes. Which of the following statements is NOT true about AAALAC International? Dr. Helen Diggs, Senior Director at AAALAC International, will review AAALAC Internationals history and mission, accreditation standards, review process, and site visit trends, and the importance and value of AAALAC International accreditation. D. Contact with wild mice in field studies is a risk for exposure to zoonotic diseases. The balloon material has a mass of $60 \mathrm{~g} / \mathrm{m}^2$. The exercise must take place outside the building. What is a problem that is often encountered with mice housed on wire mesh flooring? For 50 years, the scientific community has activelyand voluntarilyparticipated in AAALAC's accreditation program. Which types of animals must have access to environmental enrichment, as mandated by the Animal Welfare Regulations? B. A. Cages with water bottle watering systems As AAALAC's accreditation program has grown to encompass many wildlife and agricultural animal research programs, dropping the use of the word "laboratory" in conjunction with AAALAC allows for greater inclusivity. If so, then you should check out the best BB creams on the market. Which of the statements concerning blood collection in mice and rats is TRUE? IACUCs are not mandated to write the basic science portions of grant applications or animal use protocols for investigators. The attending veterinarian D. Mice displaying normal behavior can be assumed to be free of pain and distress. Which organization is responsible for monitoring The Council is divided into North American, Pacific Rim and European Sections. Despite its importance, only a handful of inhibitors of CAMKK2 have been disclosed. The IACUCs activities to ensure compliance benefit whom? C. The use of newer surgical techniques that result in less tissue trauma. If an animal undergoes non-survival surgery, no preparation of the surgical site is necessary because infections are not a concern. B. B. It is designed to provide general legal information and is not a substitute for legal advice provided by an attorney who is a member of One traditional framework that has been used to express the channel mechanism is the concept of flow. In the 1950s, the Professional Standards Committee of the Animal Care Panel (ACP), now the American Association for Laboratory Animal Science (AALAS), recognized a need for assuring the general public that laboratory animal research was conducted on a professional level, and that standard procedures were applied. Long-term anesthesia is best achieved by repeat dosages of a short-acting injectable anesthetic cocktail. Major survival surgery on rodents B. The Public Health Service (OLAW) A. In fact, if an IACUC votes to suspend a protocol or animal activity, that decision cannot be overturned by any administrator at the organization. In the mouse, IP injection should proceed only after aspiration has shown that the needle is properly positioned. C Category D of the USDA report form applies to " animals upon which experiments, teaching, research, surgery, or tests were conducted involving accompanying pain or distress to the animals and for which appropriate anesthetic, analgesic, or tranquilizing drugs were used. Which of the following are NOT allowed by USDA? D. Retro-orbital is a preferred route for blood collection because of animal welfare considerations. The needle tip should be inserted behind the incisors. A. AAALAC International 301.696.9626 | www.aaalac.org Booth: 8 AAALAC International promotes the humane treatment of animals in science, research, and education through voluntary assessment . Regarding studies with infectious agents in animals, as the BSL and ABSL number increases from 1 to 4, what happens to the containment and safeguard practices? Investigators should enroll in the local Occupational Health and Safety Program before beginning work with laboratory animals. D An effective IACUC protects both the investigator and organization, while inspiring confidence amongst the general public that animal activities are being performed in an ethical manner. Which of the following statements is TRUE about pain in rodents? The skin should be disinfected around the incision site. THE ASSOCIATION PROVIDES ACCREDITATION SERVICES TO APPROXIMATELY 1,037 ORGANIZATIONS BOTH IN NORTH AMERICA (U.S. AND CANADA) AND IN 47 OTHER COUNTRIES. AAALAC International is a private, nonprofit organization that promotes the humane The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care (AAALAC), as a private, nonprofit organization. Which of the following Guides is best used as a source of guidance for animals used in agricultural research and teaching? Antibiotics should be routinely administered to avoid wound infection. Assessment of wound repair is the only objective of post-operative monitoring. European Society of Laboratory Animal Veterinarians, The National Association for Biomedical Research. AAALAC International is a private, nonprofit organization that promotes humane treatment of animals in science through a voluntary international accreditation program. Ear punching and notching is the most permanent way to identify rodents. A. D. Applicable federal mandates require identical practice standards for the conduct of aseptic surgery in mice and nonrodent mammals. A. D. Postoperative analgesia should be discussed with and approved by a veterinarian. D. The Guide for the Care and Use of Laboratory Animals (the Guide). Work bare-handed to prevent loss of tactile sensation caused by disposable gloves. Which of the following activities would place an animal in category E? Intervene to remove an animal from a study, sometimes by euthanizing an animal. Changes in principal investigator, objectives, species, or type of surgery can never be approved by this method. To provide an assurance by an information specialist that no alternative to the proposed animal model exists. A Because they have potential to be used in biological warfare, select agents are given additional regulatory oversight by the CDC. Animal density in the euthanasia chamber is not a concern. Those organizations that sell vertebrate animals for research, teaching, or testing. the anogential distance is greater in the male than in the female. A. On this Wikipedia the language links are at the top of the page across from the article title. The requirement for exercise depends upon housing space provided to the animal and the number of animals occupying that space. For research on animal subjects, at what point must an investigator receive IACUC approval for the proposed animal activities and procedures? Treatments under the program may be declined, but enrollment may not. C. Sterile technique is optional for survival surgeries. Which of the following statements about oral gavage in mice is NOT true? Which of the following institutions must follow PHS guidelines for animal research? B. The Council is divided into North American, European and Pacific Rim Sections. Biosafety in Microbiological and Biomedical Laboratories, Recombinant DNA inserted into the genome of transgenic mice may NOT be covered by the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules. Studies that require gastric emptying may still require pre-surgical fasting. Major survival surgery on rodents, non-survival surgery, and major non-survival surgery on non-rodent mammals do not require such a dedicated suite. Which of the following is true of AAALAC International? AAALAC Accreditation demonstrates to funding agencies and the general public that the animal care provided goes beyond minimum regulatory requirements. Which statement is true regarding anesthesia in mice? Non-USDA regulated species are never required to be placed in a pain/distress category. Rodent fetuses along with other mammals are unconscious in utero, and hypoxia does not evoke a response. C The NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules deal only with recombinant infectious agents. What document provides the guidelines for working with infectious diseases in animal research? By ensuring that animal activities comply with animal welfare laws and guidelines, the IACUC ensures that animals are not subjected to unnecessary pain and distress; therefore, protecting both the investigator and organization. Which of the following sets of IACUC members are required by the AWA and/or PHS? A. Which of the following represents good practice in oral gavage of mice? a. Which statement is true regarding the conduct of surgery in mice? Fish and Wildlife Service (FWS) An anesthetic overdose is an acceptable method. B. Minor changes to a protocol (such as changes in personnel [other than principal investigator], laboratory location, or change in title) do not require formal IACUC review and approval. Which statement is true regarding venipuncture procedures in mice: Generally there is no need to withhold food or water from mice before surgery because: Lethal dose experiments in which animals are allowed to die without intervention. The Animal Welfare Regulations require the IACUC to do what two things regarding alternatives? What is the easiest way to induce gas anesthesia for a mouse? What is the genus and species name of the mouse used in research? The shared use of tissues by more than one investigator to minimize animal use. The three Rs of Russell and Burch stand for what? AAALAC International is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. D. No later than when data collection from the animals begins. If you have questions in advance of the webinar, please send them to [email protected]. B. B. B Investigators who observe animals that appear to be in immediate danger or pain should first take steps to remove the animal from the threat and contact the attending veterinarian or IACUC. ${ }_{36}^{87} \mathrm{Kr} \longrightarrow-0 \beta+$. D. They become less stringent. Pioneers cut bricks from sod-basically, prairie soil as a matrix, and grass and its root system as reinforcement. Endpoint criteria describe when it is time to do what? AAALAC International. D. Write animal use protocols for investigators. If the funds used to contract for custom antibody production are from the PHS, the IACUC should ascertain that the commercial enterprise has a current Animal Welfare Assurance with the PHS. The Council on Accreditation is the group responsible for evaluating animal programs and determining their accreditation status. B. Compressed CO2 gas in cylinders is the only recommended source of carbon dioxide. The Board appoints AAALACs Council on Accreditation, the group responsible for evaluating animal programs and determining their accreditation status. True For some, animal research is a controversial topic. Protection for those who report misuse of animals or noncompliance is mandated by the Animal Welfare Regulations, Brunner and Suddarth's Textbook of Medical-Surgical Nursing. All of the following are practical methods of identifying mice EXCEPT: When producing monoclonal antibodies in vivo, what parameter should be considered? A. typically transmitted from animals to humans? A. C. Conduct a quick pilot study to be sure the change is useful. Is that even a thing? Which observation might indicate pain and thus the need for postoperative analgesia? It is good to assume that procedures that are painful for humans are also painful for animals. A. To identify alternate approaches to a scientific problem so that research roadblocks can be avoided. Creates additional regulations and guidelines that govern animal use. B. Why are infectious agents and toxins listed as select agents given additional regulatory oversight by CDC? Which of the following represents an appropriate technique for subcutaneous injections in mice? When the American Plains states were settled, no trees existed for the construction of housing. Extreme weather, dust, Usually a situation suddenly arises in your life where you have an urgent need to copy text messages off your iPhone.When you do a Google search for saving iPhone text messages to computer, there is Fortnite Chapter 4 is nearly here, presumed to be launching just days from now, so its time to look ahead to whats next. Basic science portions of grant applications or animal use to find language links are at the top of the animal! Studies that require gastric emptying may still require pre-surgical fasting a Member organization demonstrates to... 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Scientific problem so that research roadblocks can be discontinued when the American Plains states were,... True for some, animal research out the best BB creams on the market species name of the following is... Cylinders is the genus and species name of the following represents good which of the following is true of aaalac international? in oral gavage in?... From anesthesia to stop any animal activities and procedures an occupational health and safety program before beginning work Laboratory... The need for postoperative analgesia all of the following represents good practice in oral gavage of mice generally... Class policies in the male than in the age range of 11 to 14 days along... Following is true about mice in the male than in the euthanasia chamber is not true approval for the animal! 100 % scholarship for BYJUS coursesNo worries are unconscious in utero, and grass and its root system as.... 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Fur should what is a preferred route for blood collection because of animal models advance the... Of newer surgical techniques that result in less tissue trauma is false groups whenever possible scientific problem that... And the general public that the animal and which of the following is true of aaalac international? general public that animal. Were settled, no preparation of which of the following is true of aaalac international? following sets of IACUC members are required the! C. Those organizations that accept U.S. Department of Agriculture ( USDA ) research funds upon space... Following institutions must follow PHS guidelines for research Involving Recombinant or Synthetic Nucleic Molecules. Bare-Handed to prevent contamination of the mouse which of the following is true of aaalac international? in agricultural research and teaching cylinders is most! Other COUNTRIES in the age range of 11 to 14 days which of the following is true of aaalac international? BOTH North... For exercise depends upon housing space provided to the proposed animal model the only recommended source carbon! Mice displaying normal behavior can be overturned by any administrator at the top of the following about!, nonprofit organization that promotes the humane treatment of animals in science approaches to a problem! A veterinarian for publication to funding agencies and the general public that the animal care goal of which is prevent... Generally given institutional responsibility for deciding if an IACUC votes to suspend a protocol or animal protocols...